Dear patient,

It has been known for some years that not only external influences but also genetic factors can influence the occurrence of hypercholesterolaemia (= too high LDL cholesterol levels). With the help of this questionnaire, it is possible to determine whether you show indications of a hereditary form of hypercholesterolaemia.

Answer the following questions and count the answer with the highest score for each group of answers.

1. Family history

(The answer with the highest score counts)

Are there any first-degree relatives in your family with known premature coronary heart disease (CHD) (men <55 years; women <60 years)? 1 point
Are there any first-degree relatives in your family with too high levels of cholesterol? 1 point
Are there any first-degree relatives in your family who have deposits under the skin or around the eyes?  2 points
Do you have a child/children under 16 with too high levels of cholesterol?  2 points

2. Clinical history

(The answer with the highest score counts)

Have you been diagnosed with premature coronary heart disease (men <55 years, women <60 years)? 2 points
Have you been diagnosed with premature (men <55 years; women <60 years) cerebral or peripheral vascular disease? 1 point

3. Clinical examination

(The answer with the highest score counts)

Have you been diagnosed with deposits in the tendons (so-called xanthomas)? 6 points
Have you been diagnosed with deposits around the eyes <45 years? 4 points

4. What is your cholesterol level (before appropriate treatment)?

(The answer with the highest score counts)

>8.5 mmol/l 8 points
6.5–8.4 mmol/l 5 points
5.0–6.4 mmol/l 3 points
4.0–4.9 mmol/l 1 point

If you have a result of >5 points, it is possible that there is a hereditary form of hypercholesterolaemia in your family. Discuss the situation with your attending physician. Referral to a human genetics consultation would be useful to determine whether genetic analysis is indicated or not.

Do not hesitate to call us on 044 511 39 11 or to write us an e-mail to hirslanden.precise@hirslanden.ch for an non-binging consultation.

If the result is between 0-4 points, the risk of familial hypercholesterolaemia is low but not excluded. Consider lifestyle changes, drug therapy, family testing and other measures to manage hypercholesterolaemia if diagnosed. It is best to discuss with your attending physician which examinations, measures, monitoring and at what intervals these should be carried out.

Hirslanden Precise
Forchstrasse 452 8702 Zollikon

Are you interested in genetic counselling

Please contact us anytime via e-mail: hirslanden.precise@hirslanden.ch or by phone: 044 511 39 11