Hyperactive bladder is most frequently caused by the following conditions:

  • Multiple sclerosis (MS). MS is a chronic inflammatory disease that affects the central nervous system (the brain and the spinal cord). The disease affects neurons and other nerve cells present in the brain and the spinal cord which transmit information signals and generate thoughts and perceptions. These cells are used by the brain to control the organism. More than one million people in the world are thought to be affected by MS. The progression of the disease is variable and unpredictable. MS can potentially affect all the body nerves. If the nerve lesions involve the vesical function, the patient may become incontinent, develop a hyperactive bladder or other bladder functional disturbances.
  • Interstitial cystitis. Interstitial cystitis is a non-bacterial bladder inflammation. Its principal symptom is a compelling need to urinate accompanied by intense pain. This disease can affect a person of any age, including children. It remains incurable and only its symptoms can be treated.
  • Chronic prostatitis. An estimated 35% of men develop prostatitis at least once in their lifetime. The same symptoms prevail as with hyperactive bladder; fever occurs only rarely. Patients occasionally complain about pain during ejaculation and the presence of blood in the ejaculate. Prostatodynia mainly affects men in the second to fourth decade of life. Its major symptoms include pubian and perineal pain, frequent miction, urinary urgency and pain during ejaculation.
  • Parkinson’s syndrome
  • Paraplegia
  • Metabolic neuropathies, such as diabetes-associated cystitis
  • Spina bifida