Scientific publications of research projects supported by Hirslanden Clinical Trial Unit (CTU) are available here.

Impact of respirator versus surgical masks on SARS-CoV-2 acquisition in healthcare workers: a prospective multicentre cohort.

Haller S, Güsewell S, Egger T, Scanferla G, Thoma R, Leal-Neto OB, Flury D, Brucher A, Lemmenmeier E, Möller JC, Rieder P, Rütti M, Stocker R, Vuichard-Gysin D, Wiggli B, Besold U, Kuster SP, McGeer A, Risch L, Schlegel M, Friedl A, Vernazza P, Kahlert CR, Kohler P. Impact of respirator versus surgical masks on SARS-CoV-2 acquisition in healthcare workers: a prospective multicentre cohort. Antimicrob Resist Infect Control. 2022 Feb 5;11(1):27.

DOI: 10.1186/s13756-022-01070-6

Symptoms compatible with long-COVID in healthcare workers with and without SARS-CoV-2 infection - results of a prospective multicenter cohort.

Strahm C, Seneghini M, Güsewell S, Egger T, Leal O, Brucher A, Lemmenmeier E, Meier Kleeb D, Möller JC, Rieder P, Ruetti M, Rutz R, Schmid HR, Stocker R, Vuichard-Gysin D, Wiggli B, Besold U, Kuster SP, McGeer A, Risch L, Friedl A, Schlegel M, Schmid D, Vernazza P, Kahlert CR, Kohler P. Symptoms compatible with long-COVID in healthcare workers with and without SARS-CoV-2 infection - results of a prospective multicenter cohort. Clin Infect Dis. 2022 Jan 28:ciac054.
DOI: 10.1093/cid/ciac054

Impact of baseline SARS-CoV-2 antibody status on syndromic surveillance and the risk of subsequent COVID-19-a prospective multicenter cohort study.

Kohler P, Güsewell S, Seneghini M, Egger T, Leal O, Brucher A, Lemmenmeier E, Möller JC, Rieder P, Ruetti M, Stocker R, Vuichard-Gysin D, Wiggli B, Besold U, Kuster SP, McGeer A, Risch L, Friedl A, Schlegel M, Vernazza P, Kahlert CR. Impact of baseline SARS-CoV-2 antibody status on syndromic surveillance and the risk of subsequent COVID-19-a prospective multicenter cohort study. BMC Med. 2021 Oct 14;19(1):270. 

DOI: 10.1186/s12916-021-02144-9

Non-occupational and occupational factors associated with specific SARS-CoV-2 antibodies among hospital workers - A multicentre cross-sectional study.

Kahlert CR, Persi R, Güsewell S, Egger T, Leal-Neto OB, Sumer J, Flury D, Brucher A, Lemmenmeier E, Möller JC, Rieder P, Stocker R, Vuichard-Gysin D, Wiggli B, Albrich WC, Babouee Flury B, Besold U, Fehr J, Kuster SP, McGeer A, Risch L, Schlegel M, Friedl A, Vernazza P, Kohler P. Non-occupational and occupational factors associated with specific SARS-CoV-2 antibodies among hospital workers - A multicentre cross-sectional study. Clin Microbiol Infect. 2021 Sep;27(9):1336-1344.

DOI: 10.1016/j.cmi.2021.05.014

A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease.

Schuppan D, Mäki M, Lundin KEA, Isola J, Friesing-Sosnik T, Taavela J, Popp A, Koskenpato J, Langhorst J, Hovde Ø, Lähdeaho ML, Fusco S, Schumann M, Török HP, Kupcinskas J, Zopf Y, Lohse AW, Scheinin M, Kull K, Biedermann L, Byrnes V, Stallmach A, Jahnsen J, Zeitz J, Mohrbacher R, Greinwald R; CEC-3 Trial Group. A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease. N Engl J Med. 2021 Jul 1;385(1):35-45.

DOI: 10.1056/NEJMoa2032441

 

Potentially inappropriate medications and medication combinations before, during and after hospitalizations: an analysis of pathways and determinants in the Swiss healthcare setting.

Migliazza K, Bähler C, Liedtke D, Signorell A, Boes S, Blozik E. Potentially inappropriate medications and medication combinations before, during and after hospitalizations: an analysis of pathways and determinants in the Swiss healthcare setting. BMC Health Serv Res. 2021 May 28;21(1):522. 

DOI: 10.1186/s12913-021-06550-w

Wide area transepithelial sample esophageal biopsy combined with computer assisted 3-dimensional tissue analysis (wats3d) for detection of high grade dysplasia and adenocarcinoma in barrett: European multi-center, prospective, randomized, tandem study.

Raf Bisschops, Rehan Haidry, Helmut Messmann, Krish Ragunath, Pradeep Bhandari, Alessandro Repici, Miguel Muñoz Navas, Stefan Seewald, Arnaud Lemmers, Antoni Castells, Oliver Pech, Erik.J. Schoon, Revital Kariv, Horst Neuhaus, Bas L. Weusten, Peter D. Siersema,  loredana Correale, Frank B. Fromowitz, Gert De Hertogh, Jacques Bergman, Cesare Hassan. Wide area transepithelial sample esophageal biopsy combined with computer assisted 3-dimensional tissue analysis (wats3d) for detection of high grade dysplasia and adenocarcinoma in barrett: European multi-center, prospective, randomized, tandem study. Gastrointestinal Endoscopy, Volume 91, Issue 6, Supplement, 2020, Page AB23, ISSN 0016-5107,

DOI: https://doi.org/10.1016/j.gie.2020.03.063

Arthroscopic and open treatment of cartilage lesions with BST-CARGEL scaffold and microfracture: A cohort study of consecutive patients.

Steinwachs M, Cavalcanti N, Mauuva Venkatesh Reddy S, Werner C, Tschopp D, Choudur HN. Arthroscopic and open treatment of cartilage lesions with BST-CARGEL scaffold and microfracture: A cohort study of consecutive patients. Knee. 2019 Jan;26(1):174-184.

DOI: 10.1016/j.knee.2018.11.015