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A genetic predisposition is a contributing factor in the development and progression of many diseases. At Hirslanden Precise, our centre of excellence for genetic medicine, we examine the individual genetic predispositions of our patients. This allows us to provide more precise diagnoses and more effective prevention and treatment options in many medical specialities.

Hirslanden Precise - genetic medicine
Forchstrasse 452 8702 Zollikon

Clinical uses

Genetic testing enables more individualised medicine in all specialist areas - in prevention, diagnostics and treatment. Find out below what added value genetic testing offers in the individual specialities.

Personalised prevention

Genetic tests are carried out in this area if someone is already sick and the disease is believed to be genetic in nature. The aim is to identify or exclude the genetic causes, to enable a reliable diagnosis and to support appropriate therapy. We focus in particular on common diseases such as cardiovascular disease or cancer.

Personalised development

Aside from the diagnosis and treatment of diseases, genetic analyses can potentially help to improve patients' well-being. For example, they can provide information on how personal performance or eating habits can be optimised. Patients with a genetic variant can thus plan their life better and deal with their disease. As soon as a clear relationship between the genetic findings and lifestyle has been proven, we will include this area in our offer.

Procedure of a genetic test

The procedure of a genetic examination is very simple for patients:

1. Initial consultation and family tree analysis

Together with the expert, you will discuss your individual family history. Based on this, you will jointly define the genetic analysis that is right for you. Genetic analyses are already part of the medical treatment guidelines in various areas (e.g. breast cancer and prostate cancer). This means that they are included as standard in the treatment.

The expert will inform you about your rights (e.g. right to know or not to know the results). Finally, we take your blood for genetic analysis.

You will receive an appointment for an initial consultation and family tree analysis within 2-4 weeks. 

Genetic analysis by the laboratory team

Hirslanden Precise has its own laboratory in Zollikon (ZH). This guarantees fast and easy-to-understand test results. The methods used by Hirslanden Precise are safe and reliable and in line with the latest technological and medical standards. Safety and the protection of privacy have the highest priority.

Discussion of the findings with specific recommendations for treatment actions

The expert will explain the results to you and categorise them in your overall treatment process. Together with your treating doctor, you will discuss suitable prevention and/or treatment options.

 

Where to find us

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Hirslanden Precise Laboratory for genetic medicine
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Hirslanden Precise Laboratory for Genetic Medicine
Forchstrasse 452 8702 Zollikon
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Klinik Aarau
Haus B der Hirslanden Klinik Aarau

Genetische Medizin

Hirslanden Precise
Hirslanden Klinik Aarau
Schänisweg 5001 Aarau

Distinction

7th place in the "World's Best Hospitals Switzerland 2023" ranking by Newsweek and Statista

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Klinik Hirslanden
Klinik Hirsladen aussen grün

Genetische Medizin

Hirslanden Precise Klinik Hirslanden
Witellikerstrasse 40 8032 Zürich

Distinctions

- 2nd place in the "Best Specialist Hospitals in Switzerland 2023" ranking by Handelszeitung and Statista for cardiac medicine.

- 4th place in the ranking "World's Best Hospitals Switzerland 2023" by Newsweek and Statista.

- 6th place in the "Best Specialist Hospitals in Switzerland 2023" ranking by Handelszeitung and Statista for orthopaedics.

 

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Klinik St. Anna
Klinik_St_Anna

Genetische Medizin

Hirslanden Precise Klinik St. Anna
St. Anna-Strasse 32 6006 Luzern

Distinctions

- 4th place in the "Best Specialist Hospitals in Switzerland 2023" ranking by Handelszeitung and Statista for cardiac medicine. 

- 4th place in the ranking "Best Specialist Hospitals in Switzerland 2023" by Handelszeitung and Statista for orthopaedics. 

- 11th place in the "World's Best Hospitals Switzerland 2023" ranking by Newsweek and Statista.

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Klinik Im Park
klinik-im-park-aussenaufnahme

Genetische Medizin

Hirslanden Precise Klinik Im Park
Seestrasse 220 8027 Zürich

Distinctions

- 3rd place in the "Best Specialist Hospitals in Switzerland 2023" ranking by Handelszeitung and Statista for cardiac medicine.

- 11th place in the "Best Specialist Hospitals in Switzerland 2023" ranking by Handelszeitung and Statista for orthopaedics.

- 15th place in the ranking "World's Best Hospitals Switzerland 2023" by Newsweek and Statista.

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Klinik Linde
Privatklinik Linde

Genetische Medizin

Hirslanden Precise Hirslanden Klinik Linde
Blumenrain 105 2501 Biel
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Klinik Beau-Site
hirslanden-beau-site-aussenansicht

Genetische Medizin

Hirslanden Precise Klinik Beau-Site
Schänzlihalde 11 3013 Bern

Distinctions

- 11th place in the "Best Specialist Hospitals in Switzerland 2023" ranking by Handelszeitung and Statista for cardiac medicine. 

- 25th place in the "World's Best Hospitals Switzerland 2023" ranking by Newsweek and Statista.

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Salem-Spital
Aussenansicht Salem-Spital

Genetische Medizin

Hirslanden Precise Salem-Spital
Schänzlistrasse 39 3013 Bern

Distinctions

19th place in the "Best Specialist Clinics in Switzerland 2023" ranking by Handelszeitung and Statista for orthopaedics.

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Clinique des Grangettes

FAQs

Here you will find the answers to frequently asked questions about personalised medicine. Who should have a genetic test? What are the advantages of genetic analysis? What is particularly important in a genetic test? If you have any further questions, please do not hesitate to contact us for professional genetic counselling. Contact us.

What exactly is genetic testing?

In genetic testing, specialists look at a person’s genetic material, i.e. DNA. For this purpose, a blood sample is taken from the person. In a specialised laboratory, the DNA is extracted from the blood and examined. The information stored in the DNA as a sequence of letters is then compared with a “reference DNA” and any deviations, so-called variants, are recorded. Genetic specialists then check whether the genetic changes found can impact the health of the person examined. If so, and wherever possible, preventive measures or individual treatments are then initiated. Since the measures are based on the individual genetic disposition, one also speaks of “precision medicine”.

Why should a patient have a genetic test?

In the following cases, it may make sense to carry out genetic testing. However, decisions are always made on a case-by-case basis:

  • If a patient is already ill and the disease is believed to be genetic in nature.
  • To confirm a diagnosis or to create the conditions for the right therapy.
  • To determine whether a person is a carrier for a hereditary disease with regard to life or family planning.
  • To detect gene mutations in healthy family members with a proven hereditary mutation in order to determine the risk of the disease and recommend appropriate preventive measures based on the findings. Whether genetic testing really makes sense must be determined on a case-by-case basis, and it requires professional genetic advice in advance.

What are the benefits of genetic medicine?

Complementary to traditional approaches to medicine, genetic medicine deals with the individual genetic preconditions of a person and tailors medical treatment accordingly.

In diagnostics, genetic medicine offers the advantage of detecting risks for diseases before they break out. Thus, early preventive measures can help to avoid a disease in the best case, or at least delay its onset. In treatment, the advantage offered by genetic medicine is that therapies and medicines that show no effect or major side effects based on personal genetic disposition can be avoided from the outset and replaced by effective therapies. This reflects a move away from the watering can principle – and towards precision medicine.

What is particularly important in a genetic test?

Clear questioning is essential for genetic testing. A doctor needs to know exactly what he or she is looking for and always assess the genetic findings in the context of a patient's symptoms. There are various ways of doing this. In addition, every genetic test must be accompanied by genetic counselling.

Which diseases are hereditary?

The extent to which genes influence the occurrence and course of a disease has not yet been clarified for all diseases. To date, more than 300,000 genetic changes that can have an influence on health have been identified – and new findings are added every year. In the meantime, the hereditary nature of cardiovascular diseases (including high blood pressure) and cancers (BRCA1 and BRCA2 mutations in the area of breast, ovarian and prostate cancer), but also of rarer diseases such as mucoviscidosis (cystic fibrosis), various muscular and metabolic diseases, etc., has been particularly well documented.

Is there always an unambiguous result?

The more genes are examined, the greater the probability of encountering an unknown gene variant that has not yet been described. In this case, it is referred to as a variant of unclear clinical significance. We then use different software and tools to try and find out whether it is more of a benign variant or a disease-causing variant. If the finding remains unclear, we recommend re-evaluating it in one to two years, as new findings are constantly being made.

What happens if, by chance, another disease is discovered during a genetic test?

The more genes you investigate, the greater the probability that you will find a pathogenic variant that is not related to the primary clinical question. However, in this case, patients always have the right not to know.

What are the costs for a Hirslanden Precise analysis?

Genetic analyses are covered by compulsory health insurance, provided they are classified as mandatory. According to Article 25, Paragraph 1 KVG, they must be used to diagnose or treat a disease and its consequences. Genetic counselling, like any other medical service, is billed via Tarmed. The tariff for the position «Genetic counselling» corresponds to the basic tariff for a general medical consultation.

How can patients have a genetic analysis done?

The procedure of a genetic test is very easy for patients. In this context, individual advice on genetic counselling before and after a genetic test is very important. In this way, we ensure that mere laboratory analysis does not leads to false conclusions.

Is Hirslanden Precise ethically justifiable?

Yes, because the legal basis alone, which we always use as a guide, is very strict in Switzerland. The aim of the HGTA is to prevent misuse of genetic testing or data and to ensure the quality of genetic testing. The focus is always on every person's right to self-determination. The right to know and not to know is of great importance. The protection of people incapable of judgement – including children – is also extensively regulated. For example, genetic tests may only be carried out on children if the child's health is acutely affected. The situation is different, for example, in the case of hereditary diseases that can only occur in adulthood. ln this case, parents are not allowed to order a genetic test as a precautionary measure to assess the risk. This is only possible when the child becomes capable of judgement and can therefore give his or her own consent.

Our team

Our Hirslanden Precise team consists of internationally recognised experts in genetic medicine. Based on their expertise and the close collaboration with the referring physician where applicable, we provide holistic, empathetic care and advice to our patients in the field of precision medicine. The genetic analyses are carried out in our own Precise Laboratory using the latest genome sequencing technologies. The analyses are then interpreted by our genetic experts and our team of experienced scientists.

Hirslanden Precise Team

Prof. Dr. med. Thomas Szucs, MPH, MBA, LLM.

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Co-Head Genomic Medicine Hirslanden

Prof. Dr. phil. nat. Sabina Gallati Kraemer

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Co-Head Genomic Medicine Hirslanden

Dr. Ing. Michael Thelen, PhD

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Technical laboratory manager Precise

Prof. Dr. med. Ariane Giacobino

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Medical Genetics Specialist

Dr. med. Julia Katharina Bickmann

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Medical Genetics Specialist

Janic Teutsch, MSc.

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Research Associate Genomic Medicine

Vanessa Stutz, Dipl. HF

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Biomedical analyst molecular diagnostics

Dr. Luca Jahreiss

Dr. Luca Jahreiss
Business Manager Hirslanden Precise

Dr. rer. medic. Wera Hofmann

Dr. rer. medic. Wera Hofmann
Genetic Counsellor (external consultant)

Genetic Promoters

The Precise Genetic Promoters are doctors with a particularly strong interest in genetic medicine. They have received further training from the Hirslanden Precise experts in specific workshops and offer genetic counselling in their respective specialties accordingly, while remaining in close contact with the Precise medical directors Prof. Gallati and Prof. Szucs. In addition, the Genetic Promoters are also ambassadors for Precise Medicine in their respective clinics.

For doctors

Do you suspect a genetic predisposition or an inherited disease in your patient? You can easily make a referral by e-mail or by telephone (044 511 39 11).

On our "Infohub for Genetic Promoters" you will find information, consultation documents and further training materials on genomic medicine, as well as information on the range of services offered by Hirslanden Precise. Write us a short message to get the login data.